Western blot analysis of AGTRAP over-expressed 293 cell line, cotransfected with AGTRAP Validated Chimera RNAi ( Cat # H00057085-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with AGTRAP monoclonal antibody (M02), clone 1G2 (Cat # H00057085-M02 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
This gene encodes a transmembrane protein localized to the plasma membrane and perinuclear vesicular structures. The gene product interacts with the angiotensin II type I receptor and negatively regulates angiotensin II signaling. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms. [provided by RefSeq
ATI receptor-associated protein,OTTHUMP00000002269,OTTHUMP00000002270,OTTHUMP00000002271,angiotensin II, type I receptor-associated protein