ACKR3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human ACKR3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human ACKR3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human ACKR3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CXCR7
Entrez GeneID
57007GeneBank Accession#
ACKR3Gene Name
CXCR7
Gene Alias
CMKOR1, GPR159, RDC1
Gene Description
chemokine (C-X-C motif) receptor 7
Omim ID
610376Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq
Other Designations
G protein-coupled receptor|chemokine orphan receptor 1
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Interactome
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Disease
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