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CABC1 rabbit monoclonal antibody

  • Catalog # : H00056997-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human CABC1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human CABC1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human CABC1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • CABC1
  • Gene Name:
  • CABC1
  • Gene Alias:
  • ADCK3,ARCA2,COQ8,MGC4849,SCAR9
  • Gene Description:
  • chaperone, ABC1 activity of bc1 complex homolog (S. pombe)
  • Gene Summary:
  • This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000035734,OTTHUMP00000035737,chaperone, ABC1 activity of bc1 complex like,chaperone-ABC1 (activity of bc1 complex, S.pombe)-like,chaperone-ABC1-like,coenzyme Q8 homolog
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