MCCC1 monoclonal antibody (M01), clone 2G8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MCCC1.
Immunogen
MCCC1 (NP_064551, 526 a.a. ~ 625 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
FTLQAHDQFSPFSSSSGRRLNISYTRNMTLKDGKNNVAIAVTYNHDGSYSMQIEDKTFQVLGNLYSEGDCTYLKCSVNGVASKAKLIILENTIYLFSKEG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (84)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MCCC1 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — MCCC1
Entrez GeneID
56922GeneBank Accession#
NM_020166Protein Accession#
NP_064551Gene Name
MCCC1
Gene Alias
DKFZp686B20267, FLJ25545, MCC-B, MCCA
Gene Description
methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
Gene Ontology
HyperlinkGene Summary
This gene encodes the large subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. [provided by RefSeq
Other Designations
3-methylcrotonyl-CoA carboxylase biotin-containing subunit|3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha
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Interactome
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Pathway
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Disease
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