Interferon kappa (IFNk) is critical for normal wound repair and is decreased in diabetic wounds. Sonya J Wolf, Christopher O Audu, Amrita Joshi, Aaron D denDekker, William J Melvin, Frank M Davis, Xianying Xing, Rachael Wasikowski, Lam Tsoi, Steven Kunkel, Johann E Gudjonsson, Mary X O'Riordan, J Michelle Kahlenberg, Katherine A Gallagher.JCI Insight. 2022 Mar 31;e152765. doi: 10.1172/jci.insight.152765. Online ahead of print.
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Interferon Kappa Is a Rheostat for Development of Psoriasiform Inflammation. Mehrnaz Gharaee-Kermani, Shannon N Estadt, Lam C Tsoi, Sonya J Wolf, Jianhua Liu, Xianying Xing, Jonathon Theros, Tammi J Reed, Lori Lowe, Dennis Gruszka, Nicole L Ward, Johann E Gudjonsson, J Michelle Kahlenberg.J Invest Dermatol. 2022 Jan;142(1):155-165.e3. doi: 10.1016/j.jid.2021.05.029. Epub 2021 Aug 5.
This gene encodes a member of the type I interferon family. Type I interferons are a group of related glycoproteins that play an important role in host defenses against viral infections. This protein is expressed in keratinocytes and the gene is found on chromosome 9, adjacent to the type I interferon cluster. [provided by RefSeq
Other Designations:
OTTHUMP00000021169,interferon kappa,interferon-like protein