JPH1 monoclonal antibody (M04), clone 2E6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant JPH1.
Immunogen
JPH1 (NP_065698, 501 a.a. ~ 579 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VADEQVTAIVNKPLMSKAPTKEAGAVVPQSKYSGRHHIPNPSNGELHSQYHGYYVKLNAPQHPPVDVEDGDGSSQSSSA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (79); Rat (79)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.43 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged JPH1 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — JPH1
Entrez GeneID
56704GeneBank Accession#
NM_020647Protein Accession#
NP_065698Gene Name
JPH1
Gene Alias
DKFZp762L0313, JP-1, JP1
Gene Description
junctophilin 1
Omim ID
605266Gene Ontology
HyperlinkGene Summary
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. [provided by RefSeq
Other Designations
junctophilin type1|mitsugumin72
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Interactome
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Disease
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