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Last updated: 2016/10/16
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BCCIP purified MaxPab mouse polyclonal antibody (B02P)MaxPab

  • Catalog # : H00056647-B02P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human BCCIP protein.
  • Immunogen:
  • BCCIP (NP_057651.1, 1 a.a. ~ 322 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of BCCIP expression in transfected 293T cell line (H00056647-T02) by BCCIP MaxPab polyclonal antibody.

    Lane 1: BCCIP transfected lysate(35.42 KDa).
    Lane 2: Non-transfected lysate.
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  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
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  • Gene Information
  • Gene Name:
  • Gene Alias:
  • TOK-1,TOK1
  • Gene Description:
  • BRCA2 and CDKN1A interacting protein
  • Gene Summary:
  • This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • BCCIPalpha,BCCIPbeta,BRCA2 and CDKN1A-interacting protein,BRCA2 and Cip1/p21 interacting protein,OTTHUMP00000020714,OTTHUMP00000020715,OTTHUMP00000020716,TOK-1alpha,TOK-1beta,cdk inhibitor p21 binding protein,p21- and CDK-associated protein 1
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