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Last updated: 2017/9/24

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INPP5E rabbit monoclonal antibody

  • Catalog # : H00056623-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human INPP5E peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human INPP5E is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human INPP5E peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Gene Name:
  • INPP5E
  • Gene Alias:
  • MGC117201,PPI5PIV
  • Gene Description:
  • inositol polyphosphate-5-phosphatase, 72 kDa
  • Gene Summary:
  • The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. Studies of the mouse counterpart suggest that this protein may hydrolyze phosphatidylinositol 3,4, 5-trisphosphate and phosphatidylinositol 3,5-bisphosphate on the cytoplasmic Golgi membrane and thereby regulate Golgi-vesicular trafficking. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000022575,inositol polyphosphate-5-phosphatase E,phosphatidylinositol (4,5) bisphosphate 5-phosphatase,phosphatidylinositol polyphosphate 5-phosphatase type IV
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