DIABLO monoclonal antibody (M02A), clone 4F9
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of DIABLO expression in transfected 293T cell line by DIABLO monoclonal antibody (M02A), clone 4F9.
Lane 1: DIABLO transfected lysate(27.131 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant DIABLO.
Immunogen
DIABLO (AAH11909, 119 a.a. ~ 218 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of DIABLO expression in transfected 293T cell line by DIABLO monoclonal antibody (M02A), clone 4F9.
Lane 1: DIABLO transfected lysate(27.131 KDa).
Lane 2: Non-transfected lysate.
ELISA
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Gene Info — DIABLO
Entrez GeneID
56616GeneBank Accession#
BC011909Protein Accession#
AAH11909Gene Name
DIABLO
Gene Alias
DIABLO-S, FLJ10537, FLJ25049, SMAC, SMAC3
Gene Description
diablo homolog (Drosophila)
Omim ID
605219Gene Ontology
HyperlinkGene Summary
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. [provided by RefSeq
Other Designations
0610041G12Rik|diablo|direct IAP-binding protein with low pI|mitochondrial Smac protein|second mitochondria-derived activator of caspase
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Interactome
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Disease
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