DIABLO purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
DIABLO MaxPab polyclonal antibody. Western Blot analysis of DIABLO expression in human kidney.
Western Blot (Transfected lysate)
Western Blot analysis of DIABLO expression in transfected 293T cell line (H00056616-T01) by DIABLO MaxPab polyclonal antibody.
Lane 1: DIABLO transfected lysate(26.29 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human DIABLO protein.
Immunogen
DIABLO (NP_063940.1, 1 a.a. ~ 239 a.a) full-length human protein.
Sequence
MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIAQKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
DIABLO MaxPab polyclonal antibody. Western Blot analysis of DIABLO expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of DIABLO expression in transfected 293T cell line (H00056616-T01) by DIABLO MaxPab polyclonal antibody.
Lane 1: DIABLO transfected lysate(26.29 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — DIABLO
Entrez GeneID
56616GeneBank Accession#
NM_019887.3Protein Accession#
NP_063940.1Gene Name
DIABLO
Gene Alias
DIABLO-S, FLJ10537, FLJ25049, SMAC, SMAC3
Gene Description
diablo homolog (Drosophila)
Omim ID
605219Gene Ontology
HyperlinkGene Summary
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with two of them encoding different isoforms and the other two probably not encoding a protein. [provided by RefSeq
Other Designations
0610041G12Rik|diablo|direct IAP-binding protein with low pI|mitochondrial Smac protein|second mitochondria-derived activator of caspase
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Interactome
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Disease
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