KCNQ5 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human KCNQ5 partial ORF ( NP_062816, 833 a.a. - 932 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
QNLIRSTEELNIQLSGSESSGSRGSQDFYPKWRESKLFITDEEVGPEETETDTFDAAPQPAREAAFASDSLRTGRSRSSQSICKAGESTDALSLPHVKLK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — KCNQ5
Entrez GeneID
56479GeneBank Accession#
NM_019842Protein Accession#
NP_062816Gene Name
KCNQ5
Gene Alias
Kv7.5
Gene Description
potassium voltage-gated channel, KQT-like subfamily, member 5
Omim ID
607357Gene Ontology
HyperlinkGene Summary
This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000016729|OTTHUMP00000064152|OTTHUMP00000064153|potassium channel protein
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Interactome
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Disease
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Publication Reference
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Relationship between rat retinal degeneration and potassium channel KCNQ5 expression.
Caminos E, Vaquero CF, Martinez-Galan JR.
Experimental Eye Research 2015 Feb; 131:1.
Application:Func, Antibody.
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Relationship between rat retinal degeneration and potassium channel KCNQ5 expression.
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