PRMT8 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PRMT8 full-length ORF ( NP_062828.3, 1 a.a. - 394 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MGMKHSSRCLLLRRKMAENAAESTEVNSPPSQPPQPVVPAKPVQCVHHVSTQPSCPGRGKMSKLLNPEEMTSRDYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVSNDYKMR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
71.7
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PRMT8
Entrez GeneID
56341GeneBank Accession#
NM_019854.3Protein Accession#
NP_062828.3Gene Name
PRMT8
Gene Alias
HRMT1L3, HRMT1L4
Gene Description
protein arginine methyltransferase 8
Omim ID
610086Gene Ontology
HyperlinkGene Summary
Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM
Other Designations
HMT1 hnRNP methyltransferase-like 3|HMT1 hnRNP methyltransferase-like 4|protein arginine N-methyltransferase 4|protein arginine N-methyltransferase 8
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Interactome
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Disease
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