PARD3 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human PARD3 partial ORF ( AAH11711, 181 a.a. - 290 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.73
Interspecies Antigen Sequence
Mouse (89); Rat (88)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PARD3
Entrez GeneID
56288GeneBank Accession#
BC011711Protein Accession#
AAH11711Gene Name
PARD3
Gene Alias
ASIP, Baz, Bazooka, FLJ21015, PAR3, PAR3alpha, PARD3A, SE2-5L16, SE2-5LT1, SE2-5T2
Gene Description
par-3 partitioning defective 3 homolog (C. elegans)
Omim ID
606745Gene Ontology
HyperlinkGene Summary
PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs; see MIM 606057) and GTPase-activating proteins (GAPs; see MIM 604980), interacts with a large set of effector proteins that typically contain a CDC42/RAC (MIM 602048)-interactive binding (CRIB) domain.[supplied by OMIM
Other Designations
OTTHUMP00000019428|atypical PKC isotype-specific interacting protein|partitioning-defective protein 3 homolog
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Interactome
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