PARD3 monoclonal antibody (M03), clone 4G5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PARD3.
Immunogen
PARD3 (AAH11711, 181 a.a. ~ 290 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (88)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.73 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PARD3 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — PARD3
Entrez GeneID
56288GeneBank Accession#
BC011711Protein Accession#
AAH11711Gene Name
PARD3
Gene Alias
ASIP, Baz, Bazooka, FLJ21015, PAR3, PAR3alpha, PARD3A, SE2-5L16, SE2-5LT1, SE2-5T2
Gene Description
par-3 partitioning defective 3 homolog (C. elegans)
Omim ID
606745Gene Ontology
HyperlinkGene Summary
PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange factors (GEFs; see MIM 606057) and GTPase-activating proteins (GAPs; see MIM 604980), interacts with a large set of effector proteins that typically contain a CDC42/RAC (MIM 602048)-interactive binding (CRIB) domain.[supplied by OMIM
Other Designations
OTTHUMP00000019428|atypical PKC isotype-specific interacting protein|partitioning-defective protein 3 homolog
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Interactome
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Pathway
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Disease
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