PCDHA5 monoclonal antibody (M01A), clone 1E8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PCDHA5.
Immunogen
PCDHA5 (NP_061731, 183 a.a. ~ 289 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (84)
Isotype
IgM Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.51 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PCDHA5 monoclonal antibody (M01A), clone 1E8 Western Blot analysis of PCDHA5 expression in HeLa ( Cat # L013V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — PCDHA5
Entrez GeneID
56143GeneBank Accession#
NM_018908Protein Accession#
NP_061731Gene Name
PCDHA5
Gene Alias
CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5
Gene Description
protocadherin alpha 5
Omim ID
606311Gene Ontology
HyperlinkGene Summary
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq
Other Designations
KIAA0345-like 9|ortholog of mouse CNR6
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