Products

Western Blot (Recombinant protein)

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged PCDHB3 is approximately 0.3ng/ml as a capture antibody.

ELISA

Entrez GeneID

56132

GeneBank Accession#

NM_018937

Protein Accession#

NP_061760

Gene Name

PCDHB3

Gene Alias

PCDH-BETA3

Gene Description

protocadherin beta 3

Omim ID

606329

Gene Ontology

Hyperlink

Gene Summary

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq

Other Designations

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