Products

Western Blot (Cell lysate)

PCDHGB7 polyclonal antibody (A01), Lot # 051123JC01 Western Blot analysis of PCDHGB7 expression in Jurkat ( Cat # L017V1 ).

Western Blot (Recombinant protein)

ELISA

Entrez GeneID

56099

GeneBank Accession#

NM_018927

Protein Accession#

NP_061750

Gene Name

PCDHGB7

Gene Alias

ME6, PCDH-GAMMA-B7

Gene Description

protocadherin gamma subfamily B, 7

Omim ID

606304

Gene Ontology

Hyperlink

Gene Summary

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq

Other Designations

cadherin ME6