NSFL1C purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
NSFL1C MaxPab polyclonal antibody. Western Blot analysis of NSFL1C expression in human placenta.
Western Blot (Transfected lysate)
Western Blot analysis of NSFL1C expression in transfected 293T cell line (H00055968-T02) by NSFL1C MaxPab polyclonal antibody.
Lane 1: NSFL1C transfected lysate(40.7 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to NSFL1C on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human NSFL1C protein.
Immunogen
NSFL1C (NP_057227, 1 a.a. ~ 370 a.a) full-length human protein.
Sequence
MAAERQEALREFVAVTGAEEDRARFFLESAGWDLQIALASFYEDGGDEDIVTISQATPSSVSRGTAPSDNRVTSFRDLIHDQDEDEEEEEGQRFYAGGSERSGQQIVGPPRKKSPNELVDDLFKGAKEHGAVAVERVTKSPGETSKPRPFAGGGYRLGAAPEEESAYVAGEKRQHSSQDVHVVLKLWKSGFSLDNGELRSYQDPSNAQFLESIRRGEVPAELRRLAHGGQVNLDMEDHRDEDFVKPKGAFKAFTGEGQKLGSTAPQVLSTSSPAQQAENEAKASSSILIDESEPTTNIQIRLADGGRLVQKFNHSHRISDIRLFIVDARPAMAATSFILMTTFPNKELADESQTLKEANLLNAVIVQRLT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (96)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
NSFL1C MaxPab polyclonal antibody. Western Blot analysis of NSFL1C expression in human placenta.Western Blot (Transfected lysate)
Western Blot analysis of NSFL1C expression in transfected 293T cell line (H00055968-T02) by NSFL1C MaxPab polyclonal antibody.
Lane 1: NSFL1C transfected lysate(40.7 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to NSFL1C on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — NSFL1C
Entrez GeneID
55968GeneBank Accession#
NM_016143Protein Accession#
NP_057227Gene Name
NSFL1C
Gene Alias
MGC3347, UBX1, UBXD10, UBXN2C, dJ776F14.1, p47
Gene Description
NSFL1 (p97) cofactor (p47)
Omim ID
606610Gene Ontology
HyperlinkGene Summary
N-ethylmaleimide-sensitive factor (NSF) and valosin-containing protein (p97) are two ATPases known to be involved in transport vesicle/target membrane fusion and fusions between membrane compartments. A trimer of the protein encoded by this gene binds a hexamer of cytosolic p97 and is required for p97-mediated regrowth of Golgi cisternae from mitotic Golgi fragments. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000029972|OTTHUMP00000029974|SHP1 homolog|UBX domain protein 2C|p47 protein
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Interactome
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Publication Reference
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Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB.
Sarkar B, Nishikata I, Nakahata S, Ichikawa T, Shiraga T, Saha HR, Fujii M, Tanaka Y, Shimoda K, Morishita K.
Scientific Reports 2019 Mar; 9(1):3491.
Application：WB, Human, Adult T-cell leukemia/ lymphoma (ATLL) cells.
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Degradation of p47 by autophagy contributes to CADM1 overexpression in ATLL cells through the activation of NF-κB.
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