SULF2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SULF2 full-length ORF ( AAH20962, 1 a.a. - 149 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
42.13
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SULF2
Entrez GeneID
55959GeneBank Accession#
BC020962Protein Accession#
AAH20962Gene Name
SULF2
Gene Alias
DKFZp313E091, FLJ90554, HSULF-2, KIAA1247, MGC126411
Gene Description
sulfatase 2
Omim ID
610013Gene Ontology
HyperlinkGene Summary
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM
Other Designations
OTTHUMP00000031223|extracellular sulfatase SULF-2
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