SULF2 monoclonal antibody (M01), clone 2H5
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant SULF2.
Immunogen
SULF2 (AAH20962, 1 a.a. ~ 149 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MPGLTCFTHDNQHWQTAPFWTLGPFCACTSANNNTYWCMRTINETHNFLFCEFATGFLEYFDLNTDPYQLMNAVNTLDRDVLNQLHVQLMELRSCKGYKQCNPRTRNMDLGLKDGGSYEQYRQFQRRKWPEMKRPSSKSLGQLWEGWEG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SULF2 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — SULF2
Entrez GeneID
55959GeneBank Accession#
BC020962Protein Accession#
AAH20962Gene Name
SULF2
Gene Alias
DKFZp313E091, FLJ90554, HSULF-2, KIAA1247, MGC126411
Gene Description
sulfatase 2
Omim ID
610013Gene Ontology
HyperlinkGene Summary
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM
Other Designations
OTTHUMP00000031223|extracellular sulfatase SULF-2
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