DMAP1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human DMAP1 protein.
Immunogen
DMAP1 (NP_061973.1, 1 a.a. ~ 467 a.a) full-length human protein.
Sequence
MATGADVRDILELGGPEGDAASGTISKKDIINPDKKKSKKSSETLTFKRPEGMHREVYALLYSDKKDAPPLLPSDTGQGYRTVKAKLGSKKVRPWKWMPFTNPARKDGAMFFHWRRAAEEGKDYPFARFNKTVQVPVYSEQEYQLYLHDDAWTKAETDHLFDLSRRFDLRFVVIHDRYDHQQFKKRSVEDLKERYYHICAKLANVRAVPGTDLKIPVFDAGHERRRKEQLERLYNRTPEQVAEEEYLLQELRKIEARKKEREKRSQDLQKLITAADTTAEQRRTERKAPKKKLPQKKEAEKPAVPETAGIKFPDFKSAGVTLRSQRMKLPSSVGQKKIKALEQMLLELGVELSPTPTEELVHMFNELRSDLVLLYELKQACANCEYELQMLRHRHEALARAGVLGGPATPASGPGPASAEPAVTEPGLGPDPKDTIIDVVGAPLTPNSRKRRESASSSSSVKKAKKP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (98)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of DMAP1 expression in transfected 293T cell line (H00055929-T01) by DMAP1 MaxPab polyclonal antibody.
Lane 1: DMAP1 transfected lysate(51.37 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to DMAP1 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — DMAP1
Entrez GeneID
55929GeneBank Accession#
NM_019100.4Protein Accession#
NP_061973.1Gene Name
DMAP1
Gene Alias
DKFZp686L09142, DNMAP1, DNMTAP1, EAF2, FLJ11543, KIAA1425, SWC4
Gene Description
DNA methyltransferase 1 associated protein 1
Omim ID
605077Gene Ontology
HyperlinkGene Summary
This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq
Other Designations
DNMT1 associated protein 1|OTTHUMP00000008845|OTTHUMP00000008846|OTTHUMP00000008847
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Interactome
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