ERBB2IP monoclonal antibody (M01A), clone 10G1
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More Files
- More Functions
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ERBB2IP.
Immunogen
ERBB2IP (NP_061165, 1272 a.a. ~ 1371 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
QGHELAKQEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIEHGQAVSLLKTFQNTVELIIVREVSS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (80)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ERBB2IP
Entrez GeneID
55914GeneBank Accession#
NM_018695Protein Accession#
NP_061165Gene Name
ERBB2IP
Gene Alias
ERBIN, LAP2
Gene Description
erbb2 interacting protein
Omim ID
606944Gene Ontology
HyperlinkGene Summary
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only two of them have been characterized to date. [provided by RefSeq
Other Designations
ERBB2 interacting protein|ERBB2-interacting protein|densin-180-like protein
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Interactome
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Disease
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