UNC45A rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human UNC45A peptide using ARM Technology.
Immunogen
A synthetic peptide of human UNC45A is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human UNC45A peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — UNC45A
Entrez GeneID
55898GeneBank Accession#
UNC45AGene Name
UNC45A
Gene Alias
FLJ10043, GC-UNC45, GCUNC-45, GCUNC45, IRO039700, SMAP-1, SMAP1
Gene Description
unc-45 homolog A (C. elegans)
Omim ID
611219Gene Ontology
HyperlinkGene Summary
UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]).[supplied by OMIM
Other Designations
general cell UNC45|smooth muscle cell associated protein-1
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Interactome
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