Rabbit monoclonal antibody raised against a human CENPN peptide using ARM Technology.
A synthetic peptide of human CENPN is used for rabbit immunization. Customer or Abnova will decide on the preferred peptide sequence.
Quality Control Testing:
Antibody reactive against human CENPN peptide by ELISA and mammalian transfected lysate by Western Blot.
In 1x PBS, pH 7.4
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
1. Customer may provide cell or tissue lysate for antibody screening. 2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPN is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM