CENPJ (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of CENPJ transfected lysate using rabbit polyclonal anti-CENPJ and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-CENPJ.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (81)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of CENPJ transfected lysate using rabbit polyclonal anti-CENPJ and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-CENPJ.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-CENPJ (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-CENPJ (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — CENPJ
Entrez GeneID
55835Gene Name
CENPJ
Gene Alias
BM032, CPAP, LAP, LIP1, MCPH6, MGC131581, MGC131582, MGC142222, MGC142224
Gene Description
centromere protein J
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. [provided by RefSeq
Other Designations
LAG-3-associated protein|LYST-interacting protein LIP1|LYST-interacting protein LIP7|OTTHUMP00000018137|centrosomal P4.1-associated protein
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Interactome
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Disease
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