CENPJ MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of CENPJ expression in transfected 293T cell line (H00055835-T01) by CENPJ MaxPab polyclonal antibody.
Lane 1: CENPJ transfected lysate(43.2 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of CENPJ transfected lysate using anti-CENPJ MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with CENPJ purified MaxPab mouse polyclonal antibody (B01P) (H00055835-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human CENPJ protein.
Immunogen
CENPJ (AAH24209.3, 1 a.a. ~ 372 a.a) full-length human protein.
Sequence
MRKLQKERKVFEKYTTAARTFPDKKEREEIQTLKQQIADLREDLKRKETKWSSTHSRLRSQIQMLVRENTDLREEIKVMERFRLDAWKRAEAIESSLEVEKKDKLANTSVRFQNSQISSGTQVEKYKKNYLPMQGNPPRRSKSAPPRDLGNLDKGQAASPREPLEPLNFPDPEYKEEEEDQDIQGEISHPDGKVEKVYKNGCRVILFPNGTRKEVSADGKTITVTFFNGDVKQVMPDQRVIYYYAAAQTTHTTYPEGLEVLHFSSGQIEKHYPDGRKEITFPDQTVKNLFPDGQEESIFPDGTIVRVQRDGNKLIEFNNGQRELHTAQFKRREYPDGTVKTVYANGHQETKYRSGRIRVKDKEGNVLMDTEL
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (81)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CENPJ expression in transfected 293T cell line (H00055835-T01) by CENPJ MaxPab polyclonal antibody.
Lane 1: CENPJ transfected lysate(43.2 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of CENPJ transfected lysate using anti-CENPJ MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with CENPJ purified MaxPab mouse polyclonal antibody (B01P) (H00055835-B01P). -
Gene Info — CENPJ
Entrez GeneID
55835GeneBank Accession#
BC024209.2Protein Accession#
AAH24209.3Gene Name
CENPJ
Gene Alias
BM032, CPAP, LAP, LIP1, MCPH6, MGC131581, MGC131582, MGC142222, MGC142224
Gene Description
centromere protein J
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. [provided by RefSeq
Other Designations
LAG-3-associated protein|LYST-interacting protein LIP1|LYST-interacting protein LIP7|OTTHUMP00000018137|centrosomal P4.1-associated protein
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Interactome
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Disease
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