SELS 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SELS full-length
Host
Human
Theoretical MW (kDa)
21
Interspecies Antigen Sequence
Mouse (82); Rat (83)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SELS antibody (H00055829-D01) by Western Blots.
SDS-PAGE Gel
SELS transfected lysate.
Western Blot
Lane 1: SELS transfected lysate ( 21 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SELS
Entrez GeneID
55829GeneBank Accession#
NM_018445Protein Accession#
NP_060915.2Gene Name
SELS
Gene Alias
AD-015, ADO15, MGC104346, MGC2553, SBBI8, SEPS1, VIMP
Gene Description
selenoprotein S
Omim ID
607918Gene Ontology
HyperlinkGene Summary
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
VCP-interacting membrane
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Interactome
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Disease
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