SELS MaxPab rabbit polyclonal antibody (D01)
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More Files
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Western Blot (Cell lysate)
SELS MaxPab rabbit polyclonal antibody. Western Blot analysis of SELS expression in HepG2.
Western Blot (Transfected lysate)
Western Blot analysis of SELS expression in transfected 293T cell line (H00055829-T03) by SELS MaxPab polyclonal antibody.
Lane 1: SELS transfected lysate(21 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of SELS transfected lysate using anti-SELS MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with SELS purified MaxPab mouse polyclonal antibody (B02P) (H00055829-B02P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human SELS protein.
Immunogen
SELS (NP_060915.2, 1 a.a. ~ 187 a.a) full-length human protein.
Sequence
MERQEESLSARPALETEGLRFLHTTVGSLLATYGWYIVFSCILLYVVFQKLSARLRALRQRQLDRAAAAVEPDVVVKRQEALAAARLKMQEELNAQVEKHKEKLKQLEEEKRRQKIEMWDSMQEGKSYKGNAKKPQEEDSPGPSTSSVLKRKSDRKPLRGGGYNPLSGEGGGACSWRPGRRGPSSGG
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (83)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
SELS MaxPab rabbit polyclonal antibody. Western Blot analysis of SELS expression in HepG2.Western Blot (Transfected lysate)
Western Blot analysis of SELS expression in transfected 293T cell line (H00055829-T03) by SELS MaxPab polyclonal antibody.
Lane 1: SELS transfected lysate(21 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of SELS transfected lysate using anti-SELS MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with SELS purified MaxPab mouse polyclonal antibody (B02P) (H00055829-B02P). -
Gene Info — SELS
Entrez GeneID
55829GeneBank Accession#
NM_018445Protein Accession#
NP_060915.2Gene Name
SELS
Gene Alias
AD-015, ADO15, MGC104346, MGC2553, SBBI8, SEPS1, VIMP
Gene Description
selenoprotein S
Omim ID
607918Gene Ontology
HyperlinkGene Summary
This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production, and thus play a key role in the control of the inflammatory response. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
VCP-interacting membrane
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Interactome
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Disease
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Publication Reference
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Derlin2 facilitates HRD1-mediated retro-translocation of sonic hedgehog at the endoplasmic reticulum.
Huang CH, Hsiao HT, Chu YR, Ye Y, Chen X.
The Journal of Biological Chemistry 2013 Aug; 288(35):25330.
Application：WB-Tr, Human, HEK 293T cells.
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Derlin2 facilitates HRD1-mediated retro-translocation of sonic hedgehog at the endoplasmic reticulum.
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