ST6GALNAC1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ST6GALNAC1 full-length
Host
Human
Theoretical MW (kDa)
66.11
Interspecies Antigen Sequence
Mouse (71); Rat (61)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ST6GALNAC1 antibody (H00055808-B01) by Western Blots.
SDS-PAGE Gel
ST6GALNAC1 transfected lysate.
Western Blot
Lane 1: ST6GALNAC1 transfected lysate ( 66.11 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ST6GALNAC1
Entrez GeneID
55808GeneBank Accession#
NM_018414.3Protein Accession#
NP_060884.1Gene Name
ST6GALNAC1
Gene Alias
HSY11339, SIAT7A, ST6GalNAcI, STYI
Gene Description
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
Omim ID
610138Gene Ontology
HyperlinkGene Summary
Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM
Other Designations
GalNAc alpha-2, 6-sialyltransferase I|GalNAc alpha-2, 6-sialyltransferase I, long form|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase|sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sia
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Interactome
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Pathway
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Disease
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