ST6GALNAC1 (Human) Recombinant Protein (Q01)

Catalog # H00055808-Q01

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Size:25 ug
Price: USD $ 510.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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  • Specification

    Product Description

    Human ST6GALNAC1 partial ORF ( NP_060884, 43 a.a. - 132 a.a.) recombinant protein with GST-tag at N-terminal.

    Sequence

    SRHQRTENIKERSLQSLAKPKSQAPTRARRTTIYAEPVPENNALNTQTQPKAHTTGDRGKEANQAPPEEQDKVPHTAQRAAWKSPEKEKT

    Host

    Wheat Germ (in vitro)

    Theoretical MW (kDa)

    35.64

    Interspecies Antigen Sequence

    Mouse (71); Rat (61)

    Preparation Method

    in vitro wheat germ expression system

    Purification

    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue.

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

    Note

    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — ST6GALNAC1

    Entrez GeneID

    55808

    GeneBank Accession#

    NM_018414

    Protein Accession#

    NP_060884

    Gene Name

    ST6GALNAC1

    Gene Alias

    HSY11339, SIAT7A, ST6GalNAcI, STYI

    Gene Description

    ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1

    Omim ID

    610138

    Gene Ontology

    Hyperlink

    Gene Summary

    Glycosylation of proteins affects cell-cell interaction, interactions with the matrix, and the functions of intracellular molecules. ST6GALNAC1 transfers a sialic acid, N-acetylneuraminic acid (NeuAc), in an alpha-2,6 linkage to O-linked GalNAc residues. The cancer-associated sialyl-Tn (sTn) antigen is formed by ST6GALNAC1-catalyzed sialylation of GalNAc residues on mucins (Ikehara et al., 1999 [PubMed 10536037]; Sewell et al., 2006 [PubMed 16319059]).[supplied by OMIM

    Other Designations

    GalNAc alpha-2, 6-sialyltransferase I|GalNAc alpha-2, 6-sialyltransferase I, long form|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase|sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sia

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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