EDEM2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human EDEM2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human EDEM2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human EDEM2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — EDEM2
Entrez GeneID
55741GeneBank Accession#
EDEM2Gene Name
EDEM2
Gene Alias
C20orf31, C20orf49, FLJ10783, bA4204.1
Gene Description
ER degradation enhancer, mannosidase alpha-like 2
Omim ID
610302Gene Ontology
HyperlinkGene Summary
In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM
Other Designations
ER degradation-enhancing-mannosidase-like protein 2|OTTHUMP00000030728
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Interactome
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