RNF126 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human RNF126 full-length ORF ( AAH01442, 1 a.a. - 326 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAEASPHPGRYFCHCCSVEIVPRLPDYICPRCESGFIEELPEETRSTENGSAPSTAPTDQSRPPLEHVDQHLFTLPQGYGQFAFGIFDDSFEIPTFPPGAQADDGRDPESRRERDHPSRHRYGARQPRARLTTRRATGRHEGVPTLEGIIQQLVNGIITPATIPSLGPWGVLHSNPMDYAWGANGLDAIITQLLNQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYALGERVRQLPCNHLFHDGCIVPWLEQHDSCPVCRKSLTGQNTATNPPGLTGVSFSSSSSSSSSSSPSNENATWSPLGRPQPPRPLSNLTL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
61.6
Interspecies Antigen Sequence
Mouse (94); Rat (90)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RNF126
Entrez GeneID
55658GeneBank Accession#
BC001442Protein Accession#
AAH01442Gene Name
RNF126
Gene Alias
FLJ20552, MGC1022, MGC14317
Gene Description
ring finger protein 126
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. [provided by RefSeq
Other Designations
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Interactome
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Publication Reference
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BAG6 prevents the aggregation of neurodegeneration-associated fragments of TDP43.
Yasar Arfat T Kasu, Akshaya Arva, Jess Johnson, Christin Sajan, Jasmin Manzano, Andrew Hennes, Jacy Haynes, Christopher S Brower.
iScience 2022 May; 25(5):104273.
Application:WB-Ce, Human, HEK 293T cells.
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Biophysical characterisation of the recombinant human frataxin precursor.
Castro IH, Ferrari A, Herrera MG, Noguera ME, Maso L, Benini M, Rufini A, Testi R, Costantini P, Santos J.
FEBS Open Bio 2018 Jan; 8(3):390.
Application:PI, Recombinant protein.
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E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia.
Benini M, Fortuni S, Condò I, Alfedi G, Malisan F, Toschi N, Serio D, Massaro DS, Arcuri G, Testi R, Rufini A.
Cell Reports 2017 Feb; 18(8):2007.
Application:Func, PI, WB, Recombinant protein.
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BAG6 prevents the aggregation of neurodegeneration-associated fragments of TDP43.
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