NLRP2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
NLRP2 transfected lysate.
Western Blot
Lane 1: NLRP2 transfected lysate ( 120.5 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-NLRP2 full-length
Host
Human
Theoretical MW (kDa)
120.5
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-NLRP2 antibody (H00055655-B01) by Western Blots.
SDS-PAGE Gel
NLRP2 transfected lysate.
Western Blot
Lane 1: NLRP2 transfected lysate ( 120.5 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — NLRP2
Entrez GeneID
55655GeneBank Accession#
NM_017852Protein Accession#
NP_060322Gene Name
NLRP2
Gene Alias
CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2
Gene Description
NLR family, pyrin domain containing 2
Omim ID
609364Gene Ontology
HyperlinkGene Summary
NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
Other Designations
NACHT, LRR and PYD containing protein 2|NACHT, leucine rich repeat and PYD containing 2|PYRIN-Containing APAF1-like|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2
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Interactome
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Disease
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