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Last updated: 2016/11/27

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NLRP2 rabbit monoclonal antibody

  • Catalog # : H00055655-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human NLRP2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human NLRP2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human NLRP2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • NLRP2
  • Gene Name:
  • NLRP2
  • Gene Alias:
  • CLR19.9,FLJ20510,NALP2,NBS1,PAN1,PYPAF2
  • Gene Description:
  • NLR family, pyrin domain containing 2
  • Gene Summary:
  • NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
  • Other Designations:
  • NACHT, LRR and PYD containing protein 2,NACHT, leucine rich repeat and PYD containing 2,PYRIN-Containing APAF1-like,nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 2
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