POMGNT1 monoclonal antibody (M07), clone 6C12
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant POMGNT1.
Immunogen
POMGNT1 (NP_060209, 221 a.a. ~ 318 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
FGEKHSKSPALSSWGDPVLLKTDVPLSSAEEAECHWADTELNRRRRRFCSKVEGYGSVCSCKDPTPIEFSPDPLPDNKVLNVPVAVIAGNRPNYLYRM
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to POMGNT1 on formalin-fixed paraffin-embedded human liver. [antibody concentration 3 ug/ml]ELISA
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Gene Info — POMGNT1
Entrez GeneID
55624GeneBank Accession#
NM_017739Protein Accession#
NP_060209Gene Name
POMGNT1
Gene Alias
DKFZp761B182, FLJ20277, GNTI.2, MEB, MGAT1.2
Gene Description
protein O-linked mannose beta1,2-N-acetylglucosaminyltransferase
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type II transmembrane protein that resides in the golgi. It participates in O-mannosyl glycosylation, and is specific for alpha linked terminal mannose. Mutations in this gene are associated with muscle-eye-brain (MEB) disease. Alternatively spliced transcript variants have been found for this gene
Other Designations
O-linked mannose beta1,2-N-acetylglucosaminyltransferase|OTTHUMP00000008901|UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2
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Interactome
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Pathway
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Disease
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