IL17RB (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human IL17RB partial ORF ( NP_061195, 18 a.a. - 117 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
REPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (82); Rat (50)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — IL17RB
Entrez GeneID
55540GeneBank Accession#
NM_018725Protein Accession#
NP_061195Gene Name
IL17RB
Gene Alias
CRL4, EVI27, IL17BR, IL17RH1, MGC5245
Gene Description
interleukin 17 receptor B
Omim ID
605458Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq
Other Designations
IL-17B receptor|cytokine receptor CRL4|interleukin 17 receptor homolog 1|interleukin 17B receptor
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Interactome
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Disease
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