NOLA3 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human NOLA3 partial ORF ( NP_061118.1, 1 a.a. - 64 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MFLQYYLNEQGDRVYTLKKFDPMGQQTCSAHPARFSPDDKYSRHRITIKKRFKVLMTQQPRPVL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
32.78
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NOP10
Entrez GeneID
55505GeneBank Accession#
NM_018648Protein Accession#
NP_061118.1Gene Name
NOP10
Gene Alias
MGC70651, NOLA3, NOP10P
Gene Description
NOP10 ribonucleoprotein homolog (yeast)
Omim ID
606471Gene Ontology
HyperlinkGene Summary
This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p. [provided by RefSeq
Other Designations
homolog of yeast Nop10p|nucleolar protein family A, member 3|nucleolar protein family A, member 3 (H/ACA small nucleolar RNPs)
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Interactome
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Disease
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