HES6 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human HES6 full-length ORF ( NP_061115.2, 1 a.a. - 224 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEVQAKLENAEVLELTVRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSSFQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRPW
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
50.5
Interspecies Antigen Sequence
Mouse (86); Rat (87)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — HES6
Entrez GeneID
55502GeneBank Accession#
NM_018645.3Protein Accession#
NP_061115.2Gene Name
HES6
Gene Alias
HES-6, bHLHb41, bHLHc23
Gene Description
hairy and enhancer of split 6 (Drosophila)
Omim ID
610331Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a subfamily of basic helix-loop-helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of this gene family regulate cell differentiation in numerous cell types. The protein encoded by this gene functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C-terminus. Alternatively spliced transcript variants encoding different isoforms have been described
Other Designations
hairy and enhancer of split 6
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Interactome
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Disease
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