PSARL (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human PSARL partial ORF ( NP_061092.3, 2 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.63
Interspecies Antigen Sequence
Mouse (90); Rat (89)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PARL
Entrez GeneID
55486GeneBank Accession#
NM_018622Protein Accession#
NP_061092.3Gene Name
PARL
Gene Alias
PRO2207, PSARL, PSARL1, PSENIP2, RHBDS1
Gene Description
presenilin associated, rhomboid-like
Omim ID
607858Gene Ontology
HyperlinkGene Summary
This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
mitochondrial intramembrane-cleaving protease PARL|rhomboid 7 homolog 1
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Interactome
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Disease
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