PI4KII monoclonal antibody (M01), clone 3E1
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PI4KII.
Immunogen
PI4KII (NP_060895.1, 383 a.a. ~ 477 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARSHQRSSSESYTQSFQSRKPFFS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (94)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PI4K2A is 1 ng/ml as a capture antibody.ELISA
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Gene Info — PI4K2A
Entrez GeneID
55361GeneBank Accession#
NM_018425Protein Accession#
NP_060895.1Gene Name
PI4K2A
Gene Alias
DKFZp761G1923, PI4KII, PIK42A, RP11-548K23.6
Gene Description
phosphatidylinositol 4-kinase type 2 alpha
Omim ID
609763Gene Ontology
HyperlinkGene Summary
Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001 [PubMed 11244087]).[supplied by OMIM
Other Designations
OTTHUMP00000020224|phosphatidylinositol 4-kinase type II (PI4KII)
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Interactome
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Disease
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