Immunoprecipitation of PI4K2A transfected lysate using anti-PI4K2A MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PI4KII purified MaxPab mouse polyclonal antibody (B01P) (H00055361-B01P).
Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001 [PubMed 11244087]).[supplied by OMIM
OTTHUMP00000020224,phosphatidylinositol 4-kinase type II (PI4KII)