NEIL3 (Human) Recombinant Protein (P02)
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More Files
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Specification
Product Description
Human NEIL3 full-length ORF (BAA91860.1, 1 a.a. - 605 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MVEGPGCTLNGEKIRARVLPGQAVTGVRGSALRSPQGRALRLAASTVVVSPQAAALNNDSSQNVLSLFNGYVYSGVETLGKELFMYFGPKALRIHFGMKGFIMINPLEYKYKNGASPVLEVQLTKDLICFFDSSVELRNSMESQQRIRMMKELDVCSPEFSFLRAESEVKKQKGRMLGDVLMDQNVLPGVGNIIKNEALFDSGLHPAVKVCQLTDEQIHHLMKMIRDFSILFYRCRKAGLALSKHYKVYKRPNCGQCHCRITVCRFGDNNRMTYFCPHCQKENPQHVDICKLPTRNTIISWTSSRVDHVMDSVARKSEEHWTCVVCTLINKPSSKACDACLTSRPIDSVLKSEENSTVFSHLMKYPCNTFGKPHTEVKINRKTAFGTTTLVLTDFSNKSSTLERKTKQNQILDEEFQNSPPASVCLNDIQHPSKKTTNDITQLSSKVNISPTISSESKLFSPAHKKPKTAHYSSPELKSCNPGYSNSELQINMTDGPRTLNPDSPRCSKHNRLCILRVVRKDGENKGRQFYACPLPREAQCGFFEWADLSFPFCNHGKRSTMKTVLKIGPNNGKNFFVCPLGKEKQCNFFQWAENGPGIKIIPGC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
92.95
Interspecies Antigen Sequence
Mouse (73); Rat (72)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NEIL3
Entrez GeneID
55247GeneBank Accession#
AK001720.1Protein Accession#
BAA91860.1Gene Name
NEIL3
Gene Alias
FGP2, FLJ10858, FPG2, NEI3, hFPG2, hNEI3
Gene Description
nei endonuclease VIII-like 3 (E. coli)
Omim ID
608934Gene Ontology
HyperlinkGene Summary
NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM
Other Designations
DNA glycosylase hFPG2|nei endonuclease VIII-like 3
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Interactome
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Pathway
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Disease
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