RCBTB1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human RCBTB1 full-length ORF ( AAH38104.1, 1 a.a. - 355 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MVDVGKWPIFTLLSPQEIASIRKVCVFGTSASEALYVTDNDEVFVFGLNYSNCLGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIATVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGNKNNLLSPAHIMVEKERVVEIAACHSAHTSAAKTQGGHVYMWGQCRGQSVILPHLTHFSCTDDVFACFATPAVSWRLLSVVSIVIGK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
64
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RCBTB1
Entrez GeneID
55213GeneBank Accession#
BC038104.2Protein Accession#
AAH38104.1Gene Name
RCBTB1
Gene Alias
CLLD7, CLLL7, GLP, MGC33184, RP11-185C18.1
Gene Description
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
Omim ID
607867Gene Ontology
HyperlinkGene Summary
This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq
Other Designations
GDP/GTP exchange factor (GEF)-like protein|OTTHUMP00000018413|chronic lymphocytic leukemia deletion region gene 7
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Interactome
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Disease
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