PNPO purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PNPO protein.
Immunogen
PNPO (NP_060599.1, 1 a.a. ~ 261 a.a) full-length human protein.
Sequence
MTCWLRGVTATFGRPAEWPGYLSHLCGRSAAMDLGPMRKSYRGDREAFEETHLTSLDPVKQFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKELDSNPFASLVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPDREYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQTNRLHDRIVFRRGLPTGDSPLGPMTHRGEEDWLYERLAP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (89)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PNPO expression in transfected 293T cell line (H00055163-T01) by PNPO MaxPab polyclonal antibody.
Lane 1: PNPO transfected lysate(28.71 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PNPO
Entrez GeneID
55163GeneBank Accession#
NM_018129.1Protein Accession#
NP_060599.1Gene Name
PNPO
Gene Alias
FLJ10535, PDXPO
Gene Description
pyridoxamine 5'-phosphate oxidase
Gene Ontology
HyperlinkGene Summary
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy. [provided by RefSeq
Other Designations
pyridoxal 5'-phosphate synthase|pyridoxine 5'-phosphate oxidase
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Interactome
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Disease
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