THAP1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human THAP1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKYSSICSEHFTPDCFKRECNNKLLKENAVPTIFLCTEPHDKKEDLLEPQEQLPPPPLPPPVSQVDAAIGLLMPPLQTPVNLSVFCDHNYTVEDTMHQRKRIHQLEQQVEKLRKKLKTAQQRCRRQERQLEKLKEVVHFQKEKDDVSERGYVILPNDYFEIVEVPA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — THAP1
Entrez GeneID
55145GeneBank Accession#
NM_018105.2Protein Accession#
NP_060575.1Gene Name
THAP1
Gene Alias
FLJ10477, MGC33014
Gene Description
THAP domain containing, apoptosis associated protein 1
Omim ID
609520Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
4833431A01Rik|THAP domain protein 1|nuclear proapoptotic factor
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Interactome
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Disease
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