THAP1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human THAP1 full-length ORF ( AAH21721, 1 a.a. - 213 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MVQSCSAYGCKNRYDKDKPVSFHKFPLTRPSLCKEWEAAVRRKNFKPTKYSSICSEHFTPDCFKRECNNKLLKENAVPTIFLCTEPHDKKEDLLEPQEQLPPPPLPPPVSQVDAAIGLLMPPLQTPVNLSVFCDHNYTVEDTMHQRKRIHQLEQQVEKLRKKLKTAQQRCRRQERQLEKLKEVVHFQKEKDDVSERGYVILPNDYFEIVEVPA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
49.17
Interspecies Antigen Sequence
Mouse (92); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — THAP1
Entrez GeneID
55145GeneBank Accession#
BC021721Protein Accession#
AAH21721Gene Name
THAP1
Gene Alias
FLJ10477, MGC33014
Gene Description
THAP domain containing, apoptosis associated protein 1
Omim ID
609520Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
4833431A01Rik|THAP domain protein 1|nuclear proapoptotic factor
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Interactome
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Disease
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