THAP1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human THAP1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human THAP1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human THAP1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — THAP1
Entrez GeneID
55145GeneBank Accession#
THAP1Gene Name
THAP1
Gene Alias
FLJ10477, MGC33014
Gene Description
THAP domain containing, apoptosis associated protein 1
Omim ID
609520Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
4833431A01Rik|THAP domain protein 1|nuclear proapoptotic factor
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Interactome
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Disease
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