FANCL 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-FANCL full-length
Host
Human
Theoretical MW (kDa)
41.36
Interspecies Antigen Sequence
Mouse (79); Rat (79)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-FANCL antibody (H00055120-B02) by Western Blots.
SDS-PAGE Gel
FANCL transfected lysate.
Western Blot
Lane 1: FANCL transfected lysate ( 41.36 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — FANCL
Entrez GeneID
55120GeneBank Accession#
NM_018062.2Protein Accession#
NP_060532.2Gene Name
FANCL
Gene Alias
FAAP43, FLJ10335, PHF9, POG
Gene Description
Fanconi anemia, complementation group L
Omim ID
608111Gene Ontology
HyperlinkGene Summary
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
PHD finger protein 9
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Interactome
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Pathway
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Disease
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