UBE2R2 DNAxPab
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human UBE2R2 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MAQQQMTSSQKALMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRDSKGKDKEYAEIIRKQVSATKAEAEKDGVKVPTTLAEYCIKTKVPSNDNSSDLLYDDLYDDDIDDEDEEEEDADCYDDDDSGNEES
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — UBE2R2
Entrez GeneID
54926GeneBank Accession#
NM_017811.3Protein Accession#
NP_060281.2Gene Name
UBE2R2
Gene Alias
CDC34B, FLJ20419, MGC10481, UBC3B
Gene Description
ubiquitin-conjugating enzyme E2R 2
Gene Ontology
HyperlinkGene Summary
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq
Other Designations
OTTHUMP00000000472|OTTHUMP00000021236|ubiquitin carrier protein R2|ubiquitin-conjugating enzyme UBC3B|ubiquitin-protein ligase R2
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Interactome
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Pathway
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Disease
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