UBE2R2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human UBE2R2 full-length ORF ( AAH47584, 1 a.a. - 238 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAQQQMTSSQKALMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRDSKGKDKEYAEIIRKQVSATKAEAEKDGVKVPTTLAEYCIKTKVPSNDNSSDLLYDDLYDDDIDDEDEEEEDADCYDDDDSGNEES
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
51.92
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — UBE2R2
Entrez GeneID
54926GeneBank Accession#
BC047584Protein Accession#
AAH47584Gene Name
UBE2R2
Gene Alias
CDC34B, FLJ20419, MGC10481, UBC3B
Gene Description
ubiquitin-conjugating enzyme E2R 2
Gene Ontology
HyperlinkGene Summary
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq
Other Designations
OTTHUMP00000000472|OTTHUMP00000021236|ubiquitin carrier protein R2|ubiquitin-conjugating enzyme UBC3B|ubiquitin-protein ligase R2
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Interactome
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Pathway
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Disease
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